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SEPT5 Antibody (N-term)

APR04009G Product Datasheet Protocol

货号	货期	规格 / 价格	询价
APR04009G		100 μl / ￥4950

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SEPT5 Antibody (N-term)

品牌	Leading Biology	货号	APR04009G
产品分类	Polyclonal Antibodies	研究领域
产品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SEPT5 Antibody (N-term).
分子量	42777 Da
细胞定位	Antigen Cellular Localization: Cytoplasm. Cytoplasm, cytoskeleton. Note=In platelets, found in areas surrounding alpha-granules
宿主	Rabbit
种属反应性	Human
免疫原	1-30 aa
靶点	This SEPT5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SEPT5.
亚型	Rabbit Ig
通用名	PNUTL1
基因ID	5413
UniProt ID	Q99719
功能	Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion (By similarity).
总结	This gene is a member of the septin gene family ofnucleotide binding proteins, originally described in yeast as celldivision cycle regulatory proteins. Septins are highly conserved inyeast, Drosophila, and mouse and appear to regulate cytoskeletalorganization. Disruption of septin function disturbs cytokinesisand results in large multinucleate or polyploid cells. This gene ismapped to 22q11, the region frequently deleted in DiGeorge andvelocardiofacial syndromes. A translocation involving the MLL geneand this gene has also been reported in patients with acute myeloidleukemia. Alternative splicing results in multiple transcriptvariants. The presence of a non-consensus polyA signal (AACAAT) inthis gene also results in read-through transcription into thedownstream neighboring gene (GP1BB; platelet glycoprotein Ib),whereby larger, non-coding transcripts are produced. [provided byRefSeq].
储存条件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
应用	WB, IHC-P, E
稀释方法	WB~~1:1000 IHC-P~~1:10~50
图像	Western blot analysis of lysate from human brain tissue lysate, using SEPT5 Antibody (N-term)(Cat. APR04009G). APR04009G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane. SEPT5 Antibody (N-term) (APR04009G)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SEPT5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
说明书	Product Datasheet Protocol
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