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TBX5 Antibody (N-term)

APR03999G Product Datasheet Protocol

货号	货期	规格 / 价格	询价
APR03999G		100 μl / ￥4950

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TBX5 Antibody (N-term)

品牌	Leading Biology	货号	APR03999G
产品分类	Polyclonal Antibodies	研究领域
产品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TBX5 Antibody (N-term).
分子量	57711 Da
细胞定位	Antigen Cellular Localization: Nucleus {ECO:0000255\|PROSITE- ProRule:PRU00201}
宿主	Rabbit
种属反应性	Human
免疫原	1-30 aa
靶点	This TBX5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TBX5.
亚型	Rabbit Ig
基因ID	6910
UniProt ID	Q99593
功能	Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation.
总结	This gene is a member of a phylogenetically conservedfamily of genes that share a common DNA-binding domain, the T-box.T-box genes encode transcription factors involved in the regulationof developmental processes. This gene is closely linked to relatedfamily member T-box 3 (ulnar mammary syndrome) on human chromosome12. The encoded protein may play a role in heart development andspecification of limb identity. Mutations in this gene have beenassociated with Holt-Oram syndrome, a developmental disorderaffecting the heart and upper limbs. Several transcript variantsencoding different isoforms have been described for this gene.
储存条件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
应用	WB, IHC-P, E
稀释方法	WB~~1:1000 IHC-P~~1:10~50
图像	All lanes : Anti-TBX5 Antibody (N-term) at 1:2000 dilution Lane 1: Hela whole cell lysates Lane 2: HepG2 whole cell lysates Lane 3: HL-60 whole cell lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 58 kDa Blocking/Dilution buffer: 5% NFDM/TBST. TBX5 Antibody (N-term) (Cat. APR03999G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TBX5 antibody detected the TBX5 protein (arrow). TBX5 Antibody (N-term) (APR03999G)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TBX5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
说明书	Product Datasheet Protocol
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