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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > CTDSP2 Antibody (N-term)

CTDSP2 Antibody (N-term)

货号 货期 规格 / 价格 询价
APR03956G 100 μl / ¥4950

CTDSP2 Antibody (N-term)

品牌

Leading Biology

货号

APR03956G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CTDSP2 Antibody (N-term).

分子量

30664 Da

细胞定位

Antigen Cellular Localization: Nucleus.

宿主

Rabbit

种属反应性

Human

免疫原

11-39 aa

靶点

This CTDSP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-39 amino acids from the N-terminal region of human CTDSP2.

亚型

Rabbit Ig

通用名

NIF2, OS4, SCP2

基因ID

UniProt ID

功能

Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.

总结

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:1000

图像

CTDSP2 Antibody (N-term) (Cat. APR03956G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CTDSP2 antibody detected the CTDSP2 protein (arrow).

说明书

数量

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