全部产品分类
品牌 |
Leading Biology | 货号 |
APR03953G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CSTB Antibody (Center).
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分子量 |
11140 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
10-39 aa
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靶点 |
This CSTB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the Central region of human CSTB.
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亚型 |
Rabbit Ig
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通用名 |
CST6, STFB
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基因ID |
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UniProt ID |
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功能 |
This is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B.
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总结 |
The cystatin superfamily encompasses proteins that containmultiple cystatin-like sequences. Some of the members are activecysteine protease inhibitors, while others have lost or perhapsnever acquired this inhibitory activity. There are three inhibitoryfamilies in the superfamily, including the type 1 cystatins(stefins), type 2 cystatins and kininogens. This gene encodes astefin that functions as an intracellular thiol protease inhibitor.The protein is able to form a dimer stabilized by noncovalentforces, inhibiting papain and cathepsins l, h and b. The protein isthought to play a role in protecting against the proteases leakingfrom lysosomes. Evidence indicates that mutations in this gene areresponsible for the primary defects in patients with progressivemyoclonic epilepsy (EPM1).
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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