全部产品分类
品牌 |
Leading Biology | 货号 |
APR03922G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GNAQ Antibody (N-term).
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分子量 |
42142 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Membrane. Nucleus membrane. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
52-78 aa
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靶点 |
This GNAQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-78 amino acids from the N-terminal region of human GNAQ.
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亚型 |
Rabbit Ig
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通用名 |
GAQ
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基因ID |
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UniProt ID |
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功能 |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity).
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总结 |
This locus encodes a guanine nucleotide-binding protein.The encoded protein, an alpha subunit in the Gq class, couples aseven-transmembrane domain receptor to activation of phospolipaseC-beta. Mutations at this locus have been associated with problemsin platelet activation and aggregation. A related pseudogene existson chromosome 2.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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