品牌 |
Leading Biology | 货号 |
APR03920G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality UBP46 Antibody (C-term).
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分子量 |
42442 Da
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
241-269 aa
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靶点 |
This UBP46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the C-terminal region of human UBP46.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.
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总结 |
Modification of cellular proteins by ubiquitin is anessential regulatory mechanism controlled by the coordinated actionof multiple ubiquitin-conjugating and deubiquitinating enzymes.USP46 belongs to a large family of cysteine proteases that functionas deubiquitinating enzymes (Quesada et al., 2004 [PubMed14715245]).
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
UBP46 Antibody (C-term) (Cat. APR03920G) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the UBP46 antibody detected the UBP46 protein (arrow). |
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说明书 |
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数量 |
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