全部产品分类
品牌 |
Leading Biology | 货号 |
APR03869G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Mouse Cdk3 Antibody (C-term).
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分子量 |
33888 Da
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
249-277 aa
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靶点 |
This Mouse Cdk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 amino acids from the C-terminal region of mouse Cdk3.
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亚型 |
Rabbit Ig
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通用名 |
Cdk3-ps, Cdkn3
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UniProt ID |
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功能 |
Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0- G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1- independent manner.
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总结 |
Probably involved in the control of the cell cycle. Interacts with a yet unknown type of cyclin. Can phosphorylate histone H1 (By similarity).
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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