品牌 |
Leading Biology | 货号 |
APR03864G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CELA3B Antibody (N-term).
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分子量 |
29263 Da
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
70-98 aa
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靶点 |
This CELA3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human CELA3B.
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亚型 |
Rabbit Ig
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通用名 |
ELA3B
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基因ID |
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UniProt ID |
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功能 |
Efficient protease with alanine specificity but only little elastolytic activity.
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总结 |
Elastases form a subfamily of serine proteases thathydrolyze many proteins in addition to elastin. Humans have sixelastase genes which encode the structurally similar proteinselastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase3B has little elastolytic activity. Like most of the humanelastases, elastase 3B is secreted from the pancreas as a zymogenand, like other serine proteases such as trypsin, chymotrypsin andkallikrein, it has a digestive function in the intestine. Elastase3B preferentially cleaves proteins after alanine residues. Elastase3B may also function in the intestinal transport and metabolism ofcholesterol. Both elastase 3A and elastase 3B have been referred toas protease E and as elastase 1, and excretion of this protein infecal material is frequently used as a measure of pancreaticfunction in clinical assays.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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图像 |
CELA3B Antibody (N-term) (Cat. APR03864G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CELA3B antibody detected the CELA3B protein (arrow).
CELA3B Antibody (N-term) (Cat. APR03864G)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CELA3B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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说明书 |
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数量 |
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