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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > MBL2 Antibody (C-term)

MBL2 Antibody (C-term)

货号 货期 规格 / 价格 询价
APR03857G 100 μl / ¥4950

MBL2 Antibody (C-term)

品牌

Leading Biology

货号

APR03857G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MBL2 Antibody (C-term).

分子量

26144 Da

细胞定位

Antigen Cellular Localization: Secreted.

宿主

Rabbit

种属反应性

Human

免疫原

173-202 aa

靶点

This MBL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-202 amino acids from the C-terminal region of human MBL2.

亚型

Rabbit Ig

通用名

COLEC1, MBL

基因ID

UniProt ID

功能

Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.

总结

This gene encodes the soluble mannose-binding lectin ormannose-binding protein found in serum. The protein encoded belongsto the collectin family and is an important element in the innateimmune system. The protein recognizes mannose andN-acetylglucosamine on many microorganisms, and is capable ofactivating the classical complement pathway. Deficiencies of thisgene have been associated with susceptibility to autoimmune andinfectious diseases.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IF, IHC-P, E

稀释方法

WB~~1:1000 IF~~1:10~50 IHC-P~~1:10~50

图像

MBL2 Antibody (C-term) (Cat. APR03857G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the MBL2 antibody detected the MBL2 protein (arrow).

Western blot analysis of MBL2 (arrow) using rabbit polyclonal MBL2 Antibody (C-term) (Cat. APR03857G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MBL2 gene.

Confocal immunofluorescent analysis of MBL2 Antibody (C-term)( APR03857G) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

说明书

数量

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