全部产品分类
品牌 |
Leading Biology | 货号 |
APR03829G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD3E Antibody (C-term).
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分子量 |
23147 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
154-182 aa
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靶点 |
This CD3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-182 amino acids from the C-terminal region of human CD3E.
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亚型 |
Rabbit Ig
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通用名 |
T3E
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基因ID |
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UniProt ID |
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功能 |
The CD3 complex mediates signal transduction.
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总结 |
The protein encoded by this gene is the CD3-epsilonpolypeptide, which together with CD3-gamma, -delta and -zeta, andthe T-cell receptor alpha/beta and gamma/delta heterodimers, formsthe T-cell receptor-CD3 complex. This complex plays an importantrole in coupling antigen recognition to several intracellularsignal-transduction pathways. The genes encoding the epsilon, gammaand delta polypeptides are located in the same cluster onchromosome 11. The epsilon polypeptide plays an essential role inT-cell development. Defects in this gene cause immunodeficiency.This gene has also been linked to a susceptibility to type Idiabetes in women.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
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说明书 |
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数量 |
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