全部产品分类
品牌 |
Leading Biology | 货号 |
APR03813G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PRCP Antibody (N-term).
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分子量 |
55800 Da
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细胞定位 |
Antigen Cellular Localization:
Lysosome.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
114-143 aa
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靶点 |
This PRCP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of human PRCP.
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亚型 |
Rabbit Ig
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通用名 |
PCP
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基因ID |
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UniProt ID |
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功能 |
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
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总结 |
The protein encoded by this gene is a lysosomalprolylcarboxypeptidase, which cleaves C-terminal amino acids linkedto proline in peptides such as angiotension II, III anddes-Arg9-bradykinin. The cleavage occurs at acidic pH, but theenzyme activity is retained with some substrates at neutral pH.This enzyme has been shown to be an activator of the cellmatrix-associated prekallikrein. The importance of angiotension II,one of the substrates of this enzyme, in regulating blood pressureand electrolyte balance suggests that this gene may be related toessential hypertension. Alternatively spliced transcript variantsencoding distinct isoforms have been observed. [provided byRefSeq].
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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图像 |
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说明书 |
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数量 |
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