品牌 |
Leading Biology | 货号 |
APR03797G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TRIM4 Antibody (N-term).
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分子量 |
57461 Da
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
112-141 aa
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靶点 |
This TRIM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-141 amino acids from the N-terminal region of human TRIM4.
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亚型 |
Rabbit Ig
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通用名 |
RNF87
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基因ID |
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UniProt ID |
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功能 |
E3 ubiquitin-protein ligase. Mediates 'Lys-63'-linked polyubiquitination of the innate immune receptor DDX58, this linkage doesn't lead to proteasomal degradation but seems to enhance IFN induction.
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总结 |
The protein encoded by this gene is a member of thetripartite motif (TRIM) family. The TRIM motif includes threezinc-binding domains, a RING, a B-box type 1 and a B-box type 2,and a coiled-coil region. The protein localizes to cytoplasmicbodies. Its function has not been identified. Alternatively splicedtranscript variants that encode different isoforms have beendescribed.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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图像 |
TRIM4 Antibody (N-term) (Cat. APR03797G) western blot analysis in A549,293,HepG2 cell line lysates (35ug/lane).This demonstrates the TRIM4 antibody detected the TRIM4 protein (arrow).
TRIM4 Antibody (N-term) (Cat. APR03797G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TRIM4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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说明书 |
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数量 |
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