全部产品分类
品牌 |
Leading Biology | 货号 |
APR03777G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Hrk BH3 Domain Antibody.
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分子量 |
9884 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass membrane protein. Mitochondrion
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
15-50 aa
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靶点 |
This Hrk BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-50 amino acids from human Hrk BH3 Domain.
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亚型 |
Rabbit Ig
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通用名 |
BID3
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基因ID |
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UniProt ID |
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功能 |
Promotes apoptosis.
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总结 |
Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 homology domain-3 (BH3) motif of BIK. HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXL.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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图像 |
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说明书 |
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数量 |
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