品牌 |
Leading Biology | 货号 |
APR03753G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CRHBP Antibody (N-term).
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分子量 |
36144 Da
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细胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
7-36 aa
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靶点 |
This CRHBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human CRHBP.
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亚型 |
Rabbit Ig
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通用名 |
CRFBP
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基因ID |
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UniProt ID |
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功能 |
Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
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总结 |
Corticotropin-releasing hormone is a potent stimulator ofsynthesis and secretion of preopiomelanocortin-derived peptides.Although CRH concentrations in the human peripheral circulation arenormally low, they increase throughout pregnancy and fall rapidlyafter parturition. Maternal plasma CRH probably originates from theplacenta. Human plasma contains a CRH-binding protein whichinactivates CRH and which may prevent inappropriatepituitary-adrenal stimulation in pregnancy.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
Western blot analysis of CRHBP (arrow) using rabbit polyclonal CRHBP Antibody (N-term) (Cat. APR03753G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CRHBP gene. |
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说明书 |
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数量 |
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