全部产品分类
品牌 |
Leading Biology | 货号 |
APR03712G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KLRC1 Antibody (N-term).
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分子量 |
26314 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type II membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
1-30 aa
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靶点 |
This KLRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KLRC1.
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亚型 |
Rabbit Ig
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通用名 |
NKG2A
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基因ID |
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UniProt ID |
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功能 |
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
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总结 |
Natural killer (NK) cells are lymphocytes that can mediatelysis of certain tumor cells and virus-infected cells withoutprevious activation. They can also regulate specific humoral andcell-mediated immunity. The protein encoded by this gene belongs tothe killer cell lectin-like receptor family, also called NKG2family, which is a group of transmembrane proteins preferentiallyexpressed in NK cells. This family of proteins is characterized bythe type II membrane orientation and the presence of a C-typelectin domain. This protein forms a complex with another familymember, KLRD1/CD94, and has been implicated in the recognition ofthe MHC class I HLA-E molecules in NK cells. The genes of NKG2family members form a killer cell lectin-like receptor gene clusteron chromosome 12. Four alternatively spliced transcript variantsencoding two distinct isoforms have been observed. [provided byRefSeq].
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IF, E
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稀释方法 |
WB~~1:1000
IF~~1:10~50
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图像 |
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说明书 |
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数量 |
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