全部产品分类
品牌 |
Leading Biology | 货号 |
APR03682G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PIGA Antibody (C-term).
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分子量 |
54127 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Single-pass membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
455-484 aa
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靶点 |
This PIGA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 455-484 amino acids from the C-terminal region of human PIGA.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Necessary for the synthesis of N-acetylglucosaminyl- phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis.
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总结 |
This gene encodes a protein required for synthesis ofN-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the firstintermediate in the biosynthetic pathway of GPI anchor. The GPIanchor is a glycolipid found on many blood cells and which servesto anchor proteins to the cell surface. Paroxysmal nocturnalhemoglobinuria, an acquired hematologic disorder, has been shown toresult from mutations in this gene. Alternate splice variants havebeen characterized. A related pseudogene is located on chromosome12.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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图像 |
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说明书 |
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数量 |
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