品牌 |
Leading Biology | 货号 |
APR03671G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality F2RL2 Antibody (N-term).
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分子量 |
42508 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
21-50 aa
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靶点 |
This F2RL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human F2RL2.
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亚型 |
Rabbit Ig
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通用名 |
PAR3
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基因ID |
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UniProt ID |
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功能 |
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
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总结 |
Coagulation factor II (thrombin) receptor-like 2 (F2RL2)is a member of the large family of 7-transmembrane-region receptorsthat couple to guanosine-nucleotide-binding proteins. F2RL2 is alsoa member of the protease-activated receptor family and activated bythrombin. F2RL2 is activated by proteolytic cleavage of itsextracellular amino terminus. The new amino terminus functions as atethered ligand and activates the receptor. F2RL2 is a cofactor forF2RL3 activation by thrombin. It mediates thrombin-triggeredphosphoinositide hydrolysis and is expressed in a variety oftissues.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
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图像 |
F2RL2 Antibody (N-term) (Cat. APR03671G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the F2RL2 antibody detected the F2RL2 protein (arrow).
F2RL2 Antibody (N-term) (Cat. APR03671G)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of F2RL2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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说明书 |
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数量 |
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