全部产品分类
品牌 |
Leading Biology | 货号 |
APR03608G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ID1 Antibody (Center).
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分子量 |
16133 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus.
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宿主 |
Rabbit
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种属反应性 |
Human, Rat
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免疫原 |
66-93 aa
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靶点 |
This ID1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-93 amino acids from the Central region of human ID1.
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亚型 |
Rabbit Ig
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通用名 |
BHLHB24, ID
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基因ID |
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UniProt ID |
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功能 |
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer (By similarity).
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总结 |
The protein encoded by this gene is a helix-loop-helix(HLH) protein that can form heterodimers with members of the basicHLH family of transcription factors. The encoded protein has no DNAbinding activity and therefore can inhibit the DNA binding andtranscriptional activation ability of basic HLH proteins with whichit interacts. This protein may play a role in cell growth,senescence, and differentiation. Two transcript variants encodingdifferent isoforms have been found for this gene. [provided byRefSeq].
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, FC, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:10~50
IF~~1:10~50
FC~~1:10~50
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图像 |
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说明书 |
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数量 |
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