全部产品分类
品牌 |
Leading Biology | 货号 |
APR03594G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Parp9 Antibody (C-term).
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分子量 |
96659 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytosol. Nucleus. Note=Shuttles between the nucleus and the cytosol Export to the cytosol depends on the interaction with DTX3L (By similarity). Localizes at sites of DNA damage in a PARP1-dependent manner (By similarity).
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宿主 |
Rabbit
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种属反应性 |
Mouse
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免疫原 |
599-629 aa
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靶点 |
This Parp9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 599-629 amino acids from the C-terminal region of human Parp9.
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亚型 |
Rabbit Ig
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通用名 |
Bal
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基因ID |
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UniProt ID |
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功能 |
In concert with DTX3L plays a role in PARP1-dependent DNA damage repair. PARP1-dependent PARP9/BAL1-DTX3L-mediated ubiquitination promotes the rapid and specific recruitment of 53BP1/TP53BP1, UIMC1/RAP80, and BRCA1 to DNA damage sites. Involved in inducing the expression of IFN-gamma-responsive genes (By similarity).
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总结 |
PARP9 is a novel risk related gene that is expressed at higher levels in fatal high risk diffuse large B cell lymphomas.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
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图像 |
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说明书 |
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数量 |
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