品牌 |
Leading Biology | 货号 |
APR03539G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FBXO18 Antibody (C-term).
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分子量 |
117686 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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种属反应性 |
Mouse
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免疫原 |
741-769 aa
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靶点 |
This FBXO18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 741-769 amino acids from the C-terminal region of human FBXO18.
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亚型 |
Rabbit Ig
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通用名 |
FBH1, FBX18
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基因ID |
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UniProt ID |
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功能 |
DNA-dependent ATPase. Unwinds double-stranded DNA in a 3' to 5' direction.
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总结 |
This gene encodes a member of the F-box protein family,members of which are characterized by an approximately 40 aminoacid motif, the F-box. The F-box proteins constitute one of thefour subunits of ubiquitin protein ligase complex called SCFs(SKP1-cullin-F-box), which function in phosphorylation-dependentubiquitination. The F-box proteins are divided into three classes:Fbws containing WD-40 domains, Fbls containing leucine-richrepeats, and Fbxs containing either different protein-proteininteraction modules or no recognizable motifs. The protein encodedby this gene belongs to the Fbx class. It contains an F-box motifand seven conserved helicase motifs, and has both DNA-dependentATPase and DNA unwinding activities. Alternatively splicedtranscript variants encoding distinct isoforms have been identifiedfor this gene.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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图像 |
FBXO18 Antibody (C-term) (Cat. APR03539G) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the FBXO18 antibody detected the FBXO18 protein (arrow). |
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说明书 |
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数量 |
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