全部产品分类
品牌 |
Leading Biology | 货号 |
APR03513G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PPM1L Antibody (C-term).
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分子量 |
41053 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
215-244 aa
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靶点 |
This PPM1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-244 amino acids from the C-terminal region of human PPM1L.
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亚型 |
Rabbit Ig
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通用名 |
PP2CE
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基因ID |
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UniProt ID |
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功能 |
Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.
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总结 |
PPM1L, or PP2CE, belongs to the PP2C group ofserine/threonine phosphatases, which are distinguished from otherphosphatases by their structure, absolute requirement for Mg(2+) orMn(2+), and insensitivity to okadaic acid. PP2Cs regulatestress-activated protein kinase (SAPK; see MIM 601158) signalingcascades that respond to extracellular stimuli (Jin et al., 2004[PubMed 15560375]).
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
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图像 |
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说明书 |
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数量 |
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