全部产品分类
品牌 |
Leading Biology | 货号 |
APR03467G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MPP1 Antibody (Center).
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分子量 |
52296 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Lipid-anchor. Cell projection, stereocilium. Note=Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity) Colocalizes with MPP5 in the retina, at the outer limiting membrane (OLM). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC). Colocalizes with NF2 in non- myelin-forming Schwann cells.
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
301-327 aa
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靶点 |
This MPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-327 amino acids from the Central region of human MPP1.
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亚型 |
Rabbit Ig
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通用名 |
DXS552E, EMP55
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基因ID |
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UniProt ID |
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功能 |
Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity).
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总结 |
This gene encodes the prototype of the membrane-associatedguanylate kinase (MAGUK) family proteins. MAGUKs interact with thecytoskeleton and regulate cell proliferation, signaling pathways,and intercellular junctions. The encoded protein is an extensivelypalmitoylated membrane phosphoprotein containing a PDZ domain, aSrc homology 3 (SH3) motif, and a guanylate kinase domain. Thisgene product interacts with various cytoskeletal proteins and celljunctional proteins in different tissue and cell types, and may beinvolved in the regulation of cell shape, hair cell development,neural patterning of the retina, and apico-basal polarity and tumorsuppression pathways in non-erythroid cells. Multiple transcriptvariants encoding different isoforms have been found for this gene.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, FC, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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图像 |
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说明书 |
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数量 |
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