品牌 |
Leading Biology | 货号 |
AMM02414G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality IGF2 Antibody.
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分子量 |
20140 Da
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细胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Mouse
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种属反应性 |
Human
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免疫原 |
39-68 aa
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靶点 |
This IGF2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from human IGF2.
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克隆号 |
519CT14.3.6
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亚型 |
IgM
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基因ID |
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UniProt ID |
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功能 |
The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development.
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总结 |
This gene encodes a member of the insulin family ofpolypeptide growth factors, which are involved in development andgrowth. It is an imprinted gene, expressed only from the paternalallele, and epigenetic changes at this locus are associated withWilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, andSilver-Russell syndrome. A read-through INS-IGF2 gene exists, whose5' region overlaps the INS gene and the 3' region overlaps thisgene. Alternatively spliced transcript variants encoding differentisoforms have been found for this gene.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:100~500
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图像 |
IGF2 Antibody (Cat. AMM02414G) western blot analysis in A549 cell line lysates (35μg/lane).This demonstrates the IGF2 antibody detected the IGF2 protein (arrow). |
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说明书 |
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数量 |
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