品牌 |
Leading Biology | 货号 |
AMM02353G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NLRP12 antibody (Ascites).
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分子量 |
120173 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Mouse
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种属反应性 |
Mouse
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靶点 |
This NLRP12 monoclonal antibody is generated from mouse immunized with NLRP12 recombinant protein.
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克隆号 |
228CT4.1.3
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亚型 |
IgM,K
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通用名 |
NALP12, PYPAF7, RNO
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基因ID |
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UniProt ID |
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功能 |
May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK.
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总结 |
This gene encodes a member of the CATERPILLER family ofcytoplasmic proteins. The encoded protein, which contains anN-terminal pyrin domain, a NACHT domain, a NACHT-associated domain,and a C-terminus leucine-rich repeat region, functions as anattenuating factor of inflammation by suppressing inflammatoryresponses in activated monocytes. Alternatively spliced transcriptvariants encoding distinct isoforms have been described but thefull-length nature of some of these has not been determined.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:100~1600
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图像 |
NLRP12 antibody (Cat. AMM02353G) western blot analysis in mouse cerebellum tissue lysates (35μg/lane).This demonstrates the NLRP12 antibody detected the NLRP12 protein (arrow). |
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说明书 |
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数量 |
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