全部产品分类
品牌 |
Leading Biology | 货号 |
APR00374G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BRD2 polyclonal antibody.
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分子量 |
88061 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Note=Detected on chromatin and nucleosomes
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宿主 |
Rabbit
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靶点 |
BRD2
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亚型 |
Rabbit IgG
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通用名 |
KIAA9001, RING3
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基因ID |
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UniProt ID |
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功能 |
May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.
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总结 |
Brd2, a mitogen-activated kinase localized to the nucleus, is a putative transcriptional regulator which interacts with E2F1 and with histone H4 acetylated at ‘Lys-13’. It is expressed during development and may be involved in growth control. Brd2 also may play a role in spermatogenesis or folliculogenesis and may be involved in some types of leukemia and in juvenile myoclonic epilepsy.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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说明书 |
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数量 |
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