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> 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > Aim2 (rodent) Antibody (internal region, near N-Term)品牌 |
Leading Biology | 货号 |
APG00867G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Aim2 (rodent) Antibody (internal region, near N-Term).
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分子量 |
40155 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm
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宿主 |
Goat
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亚型 |
IgG
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通用名 |
Gm1313, Ifi210
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基因ID |
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UniProt ID |
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功能 |
Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8.
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形式 |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
E
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说明书 |
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数量 |
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