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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > RAB27A Antibody (monoclonal) (M02)

RAB27A Antibody (monoclonal) (M02)

LM20884
货号 货期 规格 / 价格 询价

RAB27A Antibody (monoclonal) (M02)

品牌

Leading Biology

货号

LM20884

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

浓度

RAB27A (NP_004571, 122 a.a. ~ 221 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

1.Activated Cdc42-Bound IQGAP1 Determines the Cellular Endocytic Site.Kimura T, Yamaoka M, Taniguchi S, Okamoto M, Takei M, Ando T, Iwamatsu A, Watanabe T, Kaibuchi K, Ishizaki T, Niki IMol Cell Biol. 2013 Dec;33(24):4834-43. doi: 10.1128/MCB.00895-13. Epub 2013 Oct 7.2.Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, Garcia-Santos G, Ghajar CM, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D.Nat Med. 2012 May 27. doi: 10.1038/nm.2753.3.Stepwise Maturation of Lytic Granules during Differentiation and Activation of Human CD8+ T Lymphocytes.Sanchez-Ruiz Y, Valitutti S, Dupre L.PLoS One. 2011;6(11):e27057. Epub 2011 Nov 4.4.Synaptotagmin-like protein 1 interacts with the GTPase-activating protein Rap1GAP2 and regulates dense granule secretion in platelets.Neumuller O, Hoffmeister M, Babica J, Prelle C, Gegenbauer K, Smolenski AP.Blood. 2009 Aug 13;114(7):1396-404. Epub 2009 Jun 15.5.The GDP-dependent Rab27a effector coronin 3 controls endocytosis of secretory membrane in insulin-secreting cell lines.Kimura T, Kaneko Y, Yamada S, Ishihara H, Senda T, Iwamatsu A, Niki I.J Cell Sci. 2008 Sep 15;121(Pt 18):3092-8.

储存条件

Human

储存溶液

Ras-related protein Rab-27A, Rab-27, GTP-binding protein Ram, RAB27A, RAB27

应用

WB~~1:500~1000

数量

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