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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > RAB27A Antibody (monoclonal) (M01)

RAB27A Antibody (monoclonal) (M01)

LM20883
货号 货期 规格 / 价格 询价

RAB27A Antibody (monoclonal) (M01)

品牌

Leading Biology

货号

LM20883

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.

浓度

RAB27A (NP_004571, 122 a.a. ~ 221 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2. Ohbayashi N, et al. Pigment Cell Melanoma Res, 2010 Jun. PMID 20370853.New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496.Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India. Chattopadhyay I, et al. Mutat Res, 2010 Feb 2. PMID 20083228.Clinical presentation of Griscelli syndrome type 2 and spectrum of RAB27A mutations. Meeths M, et al. Pediatr Blood Cancer, 2010 Apr. PMID 19953648.Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity. Wood SM, et al. Blood, 2009 Nov 5. PMID 19704116.

储存条件

Human

储存溶液

Ras-related protein Rab-27A, Rab-27, GTP-binding protein Ram, RAB27A, RAB27

应用

WB~~1:500~1000

数量

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