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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > OCRL Antibody (monoclonal) (M02)

OCRL Antibody (monoclonal) (M02)

LM20738
货号 货期 规格 / 价格 询价

OCRL Antibody (monoclonal) (M02)

品牌

Leading Biology

货号

LM20738

产品分类

单克隆抗体

研究领域

产品概述

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

形式

This gene encodes a phosphatase enzyme that is involved in actin polymerization and is found in the trans-Golgi network. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease.

浓度

OCRL (NP_000267, 146 a.a. ~ 239 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

纯度

mouse

试剂准备

Clear, colorless solution in phosphate buffered saline, pH 7.2.

复溶

Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1. Swan LE, et al. Proc Natl Acad Sci U S A, 2010 Feb 23. PMID 20133602.Development of a multiplex ligation-dependent probe amplification (MLPA) assay for quantification of the OCRL1 gene. Coutton C, et al. Clin Biochem, 2010 Apr. PMID 20043897.OCRL1 function in renal epithelial membrane traffic. Cui S, et al. Am J Physiol Renal Physiol, 2010 Feb. PMID 19940034.Lowe syndrome patient fibroblasts display Ocrl1-specific cell migration defects that cannot be rescued by the homologous Inpp5b phosphatase. Coon BG, et al. Hum Mol Genet, 2009 Dec 1. PMID 19700499.Locus heterogeneity of Dent's disease: OCRL1 and TMEM27 genes in patients with no CLCN5 mutations. Tosetto E, et al. Pediatr Nephrol, 2009 Oct. PMID 19582483.

储存条件

Human

储存溶液

Inositol polyphosphate 5-phosphatase OCRL-1, Lowe oculocerebrorenal syndrome protein, OCRL, INPP5F, OCRL1

应用

WB~~1:500~1000

数量

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