全部产品分类
品牌 |
Leading Biology | 货号 |
LM20737 |
产品分类 |
单克隆抗体 | 研究领域 |
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形式 |
Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5- tetrakisphosphate to inositol 1,3,4-trisphosphate. May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly.
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浓度 |
Human OCRL |
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纯度 |
Mouse |
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复溶 |
Attree O.,et al.Nature 358:239-242(1992).
Attree O.,et al.Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
Nussbaum R.L.,et al.Hum. Genet. 99:145-150(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).
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储存条件 |
Human
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储存溶液 |
Inositol polyphosphate 5-phosphatase OCRL-1, 3.1.3.36, Lowe oculocerebrorenal syndrome protein, OCRL, INPP5F, OCRL1
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应用 |
IHC-P (5 μg/ml), WB (1:500-1:1000),
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产品描述 |
Function
Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5- tetrakisphosphate to inositol 1,3,4-trisphosphate. May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly.
Cellular_Location
Cytoplasmic vesicle, phagosome membrane. Early endosome membrane. Membrane, clathrin-coated pit. Cell projection, cilium, photoreceptor outer segment Cytoplasmic vesicle. Endosome. Golgi apparatus, trans-Golgi network. Note=Also found on macropinosomes
Tissue_Location
Brain, skeletal muscle, heart, kidney, lung, placenta and fibroblasts. Expressed in the retina and the retinal pigment epithelium.
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数量 |
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