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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > KLF4 Antibody

KLF4 Antibody

LM20540
货号 货期 规格 / 价格 询价

KLF4 Antibody

品牌

Leading Biology

货号

LM20540

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

纯度

Mouse

复溶

1. Mol Cell Proteomics. 2008 Mar;7(3):499-508. 2. J Cancer Res Clin Oncol. 2008 Aug;134(8):891-8.

储存条件

Human

储存溶液

Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4, EZF, GKLF

应用

WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000 IF~~1/200 - 1/1000

产品描述

Function Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription. Cellular_Location Nucleus.

数量

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