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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > CDX2 Antibody

CDX2 Antibody

LM20166
货号 货期 规格 / 价格 询价

CDX2 Antibody

品牌

Leading Biology

货号

LM20166

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

The caudal-related homeodomain protein 2, CDX-2, is a transcription factor which is expressed in the intestine and is thought to play an important role in the proliferation and differentiation of intestinal epithelial cells. The CDX-2 protein is expressed in primary and metastatic colorectal carcinomas, intestinal metaplasia of the stomach and intestinal type gastric cancer. In human colorectal cancer, the expression of both CDX2 and carbonic anhydrase 1, a gene regulated by CDX2, is reduced or absent. (1). CDX-2 is one of the important regulators in defining pathways for coordinate control of drug metabolism in the gastrointestinal tract (2).

浓度

A synthetic peptide corresponding to residues near the N-terminus of human CDX-2 was used as an immunogen.

纯度

Rabbit

试剂准备

50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

复溶

1. Drummond F, et al. Ann Hum Genet 61(5):393-400<br>2. Gregory PA, et al. Pharmacogenet Genomics 16(7):527-36, 2006<br>

储存条件

Human

储存溶液

Homeobox protein CDX-2, CDX-3, Caudal-type homeobox protein 2, CDX2, CDX3

应用

WB~~1:2000 IHC~~1:250~500

产品描述

Function Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Cellular_Location Nucleus.

数量

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