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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > CDX1 Antibody

CDX1 Antibody

LM20165
货号 货期 规格 / 价格 询价

CDX1 Antibody

品牌

Leading Biology

货号

LM20165

产品分类

单克隆抗体

研究领域

产品概述

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

形式

This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments. ;

纯度

Mouse

复溶

1. Am J Pathol. 2012 Aug;181(2):487-98. 2. J Korean Med Sci. 2011 May;26(5):647-53.

储存条件

Human

储存溶液

Homeobox protein CDX-1, Caudal-type homeobox protein 1, CDX1

应用

E~~1/10000 WB~~1/500 - 1/2000

产品描述

Function Could play a role in the terminal differentiation of the intestine. Cellular_Location Nucleus. Tissue_Location Intestinal epithelium.

数量

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