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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > 单克隆抗体 > CD2 Antibody [Clone BH1]

CD2 Antibody [Clone BH1]

LM20141
货号 货期 规格 / 价格 询价

CD2 Antibody [Clone BH1]

品牌

Leading Biology

货号

LM20141

产品分类

单克隆抗体

研究领域

产品概述

Store at 2 to 8°C.Antibody is stable for 24 months.

形式

CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

浓度

Human CD2 protein

纯度

Mouse

试剂准备

0.5 ml at 200ug/ml; Conjugated to AF488

复溶

1. Wang MY et. al. An effective immuno-magnetic method for bone marrow purging in T cell malignancies. Bone Marrow Transplant. 1992;9(5):319-23.

储存条件

Human

储存溶液

T-cell surface antigen CD2, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5, CD2, CD2, SRBC

产品描述

Function CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function. Cellular_Location Membrane; Single-pass type I membrane protein

数量

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