全部产品分类
品牌 |
Leading Biology | 货号 |
LM20140 |
产品分类 |
单克隆抗体 | 研究领域 |
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产品概述 |
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
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形式 |
T-cell surface antigen CD2 (CD2) is a T-cell specific surface glycoprotein that is critically important for mediating adherence of T cells to antigen-presenting cells or target cells (1). It interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, and the cytoplasmic domain is implicated in the signaling function (2). CD2 is one of the largest T-cell markers, being present on more than 95% of thymocytes; it is also found one some natural killer cells but not on B lymphocytes (3).
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浓度 |
A synthetic peptide corresponding to residues in human CD2 was used as an immunogen. |
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纯度 |
Rabbit |
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试剂准备 |
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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复溶 |
1. Withka J.M., et al. Structure 1:69-81, 1993 2. The UniProt Consortium, The Universal Protein Resource (UniProt). Nucleic Acids Res. 36:D190-D195 (2008) 3. Sewell, W. A.Proc. Nat. Acad. Sci. 83: 8718-8722, 1986
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储存条件 |
Human
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储存溶液 |
T-cell surface antigen CD2, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5, CD2, CD2, SRBC
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应用 |
WB~~1:1000~5000
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产品描述 |
Function
CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T- cells, the cytoplasmic domain is implicated in the signaling function.
Cellular_Location
Membrane; Single-pass type I membrane protein
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数量 |
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