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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > 4E-BP1 Antibody

4E-BP1 Antibody

货号 货期 规格 / 价格 询价
APR14748G 100 μl / ¥5450

4E-BP1 Antibody

品牌

Leading Biology

货号

APR14748G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality 4E-BP1 antibody.

分子量

12580 Da

宿主

Mouse

种属反应性

Human

克隆号

4B6G10

亚型

IgG1

基因ID

UniProt ID

功能

Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.

形式

Liquid. In PBS containing 0.02% sodium azide.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC, E

稀释方法

WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000

别名

Eukaryotic translation initiation factor 4E-binding protein 1, 4E-BP1, eIF4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I, EIF4EBP1

图像

Figure 1: Western blot analysis using 4E-BP1 mouse mAb against truncated 4E-BP1 recombinant protein(1)and A431 cell lysate (2).

Figure 2: Immunohistochemical analysis of paraffin-embedded human pancreas carcinoma (A), esophagus carcinoma tissue (B) and ovary tumor tissue (C), showing cytoplasmic and membrane localization using 4E-BP1 mouse mAb with DAB staining.

说明书

数量

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