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Functional Rab6-GTP Antibody, mAb (recombinant)品牌 |
Leading Biology | 货号 |
APR16045G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Functional Rab6-GTP antibody, mAb (recombinant).
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分子量 |
23593 Da
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细胞定位 |
Antigen Cellular Localization:
Golgi apparatus. Golgi apparatus membrane; Lipid- anchor
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宿主 |
Purified From?HEK 293 Cell?culture Supernatant.
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种属反应性 |
Human, Mouse, Drosophila
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靶点 |
Recognizes human, mouse and Drosophila GTP-bound Rab6a and Rab6b and mutant Rab6Q72L. Does not detect Rab6?GDP.
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克隆号 |
AA2
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亚型 |
Human IgG2λ
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通用名 |
RAB6
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基因ID |
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UniProt ID |
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功能 |
Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity.
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总结 |
Rab6 is involved in protein transport. It is a regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER).
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形式 |
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
ICC
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别名 |
Ras-related Protein Rab-6
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图像 |
Rab6-GTP is detected by immunocytochemistry using anti-Rab6-GTP, mAb (AA2). Method: HeLa cells are grown in standard culture conditions, fixed with paraformaldehyde (3%), permeablized in PBS+ BSA 0.2 % + Saponin 0.05 % and incubated with anti-Rab6-GTP, mAb (AA2) (1ug /ml) in PBS-BSA-Saponin. After incubation for 30 min at RT and several washes in PBS, cells are treated with a goat anti-human (Cy3) antibody in PBS-BSA-Saponin for 30 min at RT, washed and mounted in Moewiol. Nuclei are stained with DAPI. Picture courtesy of Dr Moutel, Dr Franck Perez Lab, Curie Institute, Paris. |
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说明书 |
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数量 |
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