全部产品分类
品牌 |
Leading Biology | 货号 |
APR13408G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SMO / Smoothened antibody (clone 3D10).
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分子量 |
86kDa
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细胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein. Cell projection, cilium
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宿主 |
Mouse
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种属反应性 |
Human
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靶点 |
Human SMO / Smoothened
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克隆号 |
3D10
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通用名 |
SMOH
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基因ID |
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UniProt ID |
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功能 |
G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
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总结 |
G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
IHC-P (5 μg/ml)
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别名 |
Smoothened homolog, SMO, Protein Gx, SMO, SMOH
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图像 |
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说明书 |
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数量 |
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