品牌 |
Leading Biology | 货号 |
APR17655G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality OCRL antibody (clone 4A6).
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分子量 |
104kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasmic vesicle, phagosome membrane. Early endosome membrane. Membrane, clathrin-coated pit. Cell projection, cilium, photoreceptor outer segment Cytoplasmic vesicle. Endosome. Golgi apparatus, trans-Golgi network. Note=Also found on macropinosomes
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宿主 |
Mouse
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种属反应性 |
Human
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靶点 |
Human OCRL
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克隆号 |
4A6
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通用名 |
INPP5F, OCRL1
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基因ID |
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UniProt ID |
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功能 |
Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5- tetrakisphosphate to inositol 1,3,4-trisphosphate. May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly.
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总结 |
Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5- trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5- tetrakisphosphate to inositol 1,3,4-trisphosphate. May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
IHC-P (5 μg/ml), WB (1:500-1:1000),
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别名 |
Inositol polyphosphate 5-phosphatase OCRL-1, 3.1.3.36, Lowe oculocerebrorenal syndrome protein, OCRL, INPP5F, OCRL1
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图像 |
Western blot of OCRL expression in transfected 293T cell line by OCRL monoclonal antibody APR17655G. |
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说明书 |
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数量 |
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