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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > MECP2 Antibody (clone 4B6)

MECP2 Antibody (clone 4B6)

货号 货期 规格 / 价格 询价
AMM06349G 50 μg / ¥5450

MECP2 Antibody (clone 4B6)

品牌

Leading Biology

货号

AMM06349G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MECP2 antibody (clone 4B6).

分子量

52kDa

细胞定位

Antigen Cellular Localization: Nucleus. Note=Colocalized with methyl-CpG in the genome

宿主

Mouse

种属反应性

Human, Mouse, Rat

靶点

Human MeCP2

克隆号

4B6

基因ID

UniProt ID

功能

Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC) (By similarity).

总结

Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC) (By similarity).

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, E

稀释方法

IHC-P (5 μg/ml), WB (1:500-1:1000),

别名

Methyl-CpG-binding protein 2, MeCp-2 protein, MeCp2, MECP2

图像

MECP2 monoclonal antibody clone 4B6. Western blot of MECP2 expression in rat muscle.

说明书

数量

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