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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > PRPK / TP53RK Antibody (clone 4B9-1H3)

PRPK / TP53RK Antibody (clone 4B9-1H3)

货号 货期 规格 / 价格 询价
AMM07354G 50 μg / ¥5450

PRPK / TP53RK Antibody (clone 4B9-1H3)

品牌

Leading Biology

货号

AMM07354G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRPK / TP53RK antibody (clone 4B9-1H3).

分子量

28kDa

细胞定位

Antigen Cellular Localization: Nucleus.

宿主

Mouse

种属反应性

Human

克隆号

4B9-1H3

通用名

C20orf64, PRPK

基因ID

UniProt ID

功能

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP (By similarity). Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation.

总结

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TP53RK has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit OSGEP (By similarity). Atypical protein kinase that phosphorylates 'Ser-15' of p53/TP53 protein and may therefore participate in its activation.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, E

稀释方法

IHC-P (10 μg/ml)

别名

TP53-regulating kinase, 2.7.11.1, Atypical serine/threonine protein kinase TP53RK, EKC/KEOPS complex subunit TP53RK, 3.6.-.-, Nori-2, p53-related protein kinase, TP53RK, C20orf64, PRPK

图像

Anti-TP53RK antibody IHC of human testis.

说明书

数量

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