全部产品分类
品牌 |
Leading Biology | 货号 |
AMM07004G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality EDEM2 antibody (clone 2E4).
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分子量 |
65kDa
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细胞定位 |
Antigen Cellular Localization:
Secreted. Endoplasmic reticulum lumen.
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宿主 |
Mouse
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种属反应性 |
Human
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克隆号 |
2.00E+04
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通用名 |
C20orf31, C20orf49
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基因ID |
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UniProt ID |
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功能 |
Initiates the endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2 (PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
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总结 |
Initiates the endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2 (PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
IHC-P (2.5 μg/ml)
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别名 |
ER degradation-enhancing alpha-mannosidase-like protein 2, EDEM2, C20orf31, C20orf49
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图像 |
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说明书 |
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数量 |
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