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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > HNRNP-E2 / PCBP2 Antibody (clone 5F12)

HNRNP-E2 / PCBP2 Antibody (clone 5F12)

货号 货期 规格 / 价格 询价
AMM05385G 50 μg / ¥5450

HNRNP-E2 / PCBP2 Antibody (clone 5F12)

品牌

Leading Biology

货号

AMM05385G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HNRNP-E2 / PCBP2 antibody (clone 5F12).

分子量

39kDa

细胞定位

Antigen Cellular Localization: Nucleus. Cytoplasm. Note=Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm

宿主

Mouse

种属反应性

Human

克隆号

5F12

基因ID

UniProt ID

功能

Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation.

总结

Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, IF, E, RNAi

稀释方法

IF (10 μg/ml), IHC-P (5 μg/ml),

别名

Poly(rC)-binding protein 2, Alpha-CP2, Heterogeneous nuclear ribonucleoprotein E2, hnRNP E2, PCBP2

图像

Western blot of PCBP2 expression in transfected 293T cell line by PCBP2 monoclonal antibody...

PCBP2 monoclonal antibody clone 5F12 Western blot of PCBP2 expression in K-562.

Immunofluorescence of monoclonal antibody to PCBP2 on HeLa cell (antibody concentration 10 ug/ml).

说明书

数量

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