> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > SFN / Stratifin / 14-3-3 Sigma Antibody (clone 3C3)品牌 |
Leading Biology | 货号 |
APR13297G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SFN / Stratifin / 14-3-3 Sigma antibody (clone 3C3).
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分子量 |
28kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Secreted. Note=May be secreted by a non-classical secretory pathway
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宿主 |
Mouse
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种属反应性 |
Human
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克隆号 |
3C3
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通用名 |
HME1
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基因ID |
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UniProt ID |
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功能 |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
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总结 |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P
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稀释方法 |
IHC-P (5 μg/ml)
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别名 |
14-3-3 protein sigma, Epithelial cell marker protein 1, Stratifin, SFN, HME1
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图像 |
SFN monoclonal antibody, clone 3C3 Western blot of SFN expression in HeLa.
Anti-SFN / 14-3-3 Sigma antibody IHC of human skin.
Anti-SFN / 14-3-3 Sigma antibody IHC of human thymus. |
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说明书 |
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数量 |
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