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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > Alpha II Spectrin Antibody

Alpha II Spectrin Antibody

货号 货期 规格 / 价格 询价
APR14917G 100 μl / ¥5450

Alpha II Spectrin Antibody

品牌

Leading Biology

货号

APR14917G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Alpha II Spectrin antibody.

分子量

240 KDa

宿主

Mouse

种属反应性

Bovine, Human, Rat

靶点

Recombinant contstruct containing the 7th, 8th, 9th repeats of human alpha II spectrin.

克隆号

3D7

亚型

IgG1

UniProt ID

总结

The spectrin family of cytoskeletal proteins is comprised of 2 alpha genes (α1 and α2) and five beta genes (β1-β5). Spectrins have been shown to function as scaffolding proteins in mechanical support of the plasma membrane as well as bind other membrane proteins and lipids (Bennett and Baines 2001). Defects in spectrin genes have been linked to some forms of hereditary spherocytosis, a type of auto-hemolytic anemia which is characterized by spherical red blood cells that are more prone to lysis (Eber and Lux 2004).

形式

Affinity purified from tissue culture supernatant.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IF

稀释方法

WB~~ 1:3000 IF~~ 1:500

别名

Spectrin alpha chain, non-erythrocytic 1, Alpha-II spectrin, Fodrin alpha chain, Spectrin, non-erythroid alpha subunit, SPTAN1, NEAS, SPTA2

图像

Western blot of rat hippocampal lysate showing specific immunolabeling of the ~240k alpha II spectrin protein.

Immunofluorescence of cultured rat neurons and glia showing axonal and dendritic staining of alpha II spectrin (green) revealing the submembraneous cytoskeleton and DNA (blue).

说明书

数量

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