品牌 |
Leading Biology | 货号 |
AMM06646G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Neuropilin-1 antibody.
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分子量 |
103.1kDa
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein
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宿主 |
Mouse
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种属反应性 |
Human
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克隆号 |
5B1E11
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亚型 |
IgG1
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通用名 |
NRP, VEGF165R
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基因ID |
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UniProt ID |
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功能 |
The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, FC, ICC, E
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稀释方法 |
E~~1/10000
FC~~1/200 - 1/400
WB~~1/500 - 1/2000
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别名 |
Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, CD304, NRP1, NRP, VEGF165R
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图像 |
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 2:Flow cytometric analysis of Hela cells using Neuropilin-1 mouse mAb (green) and negative control (red).
Figure 3:Western blot analysis using Neuropilin-1 mouse mAb against Jurkat (1), Hela (2), and HUVEC (3) cell lysate. |
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说明书 |
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数量 |
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