品牌 |
Leading Biology | 货号 |
APR10446G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality THAP1 antibody.
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分子量 |
24.9kDa
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细胞定位 |
Antigen Cellular Localization:
Nucleus, nucleoplasm. Nucleus, PML body
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宿主 |
Mouse
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种属反应性 |
Human
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克隆号 |
2F1B4
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亚型 |
IgG1
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基因ID |
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UniProt ID |
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功能 |
DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptopic activity by potentiating both serum-withdrawal and TNF-induced apoptosis.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, FC, ICC, E
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稀释方法 |
E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
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别名 |
THAP domain-containing protein 1, THAP1
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图像 |
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 2:Western blot analysis using THAP1 mAb against human THAP1 (AA: 1-213) recombinant protein. (Expected MW is 50.3 kDa)
Figure 3:Western blot analysis using THAP1 mAb against HEK293 (1) and THAP1 (AA: 1-213)-hIgGFc transfected HEK293 (2) cell lysate. |
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说明书 |
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数量 |
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