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LDLR Antibody

APR08184G Product Datasheet Protocol

货号	货期	规格 / 价格	询价
APR08184G		100 μl / ￥5450

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LDLR Antibody

品牌	Leading Biology	货号	APR08184G
产品分类	Monoclonal Antibodies	研究领域
产品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LDLR antibody.
分子量	95.4kDa
细胞定位	Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Endomembrane system; Single-pass type I membrane protein Membrane, clathrin-coated pit; Single-pass type I membrane protein. Golgi apparatus. Early endosome. Late endosome. Cell surface. Lysosome. Note=Found distributed from the plasma membrane to intracellular compartments. Localizes to the Golgi apparatus, early and late endosomes/lysosomes and cell surface in the presence of PCSK9
宿主	Mouse
种属反应性	Human
克隆号	7H5B11
亚型	IgG1
基因ID	3949
UniProt ID	P01130
功能	Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.
形式	Liquid. In PBS containing 0.02% sodium azide.
储存条件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
应用	WB, IHC, FC, ICC, E
稀释方法	E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400
别名	Low-density lipoprotein receptor, LDL receptor, LDLR
图像	Figure 1:Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); Figure 2:Western blot analysis using LDLR mAb against human LDLR (AA: 22-150) recombinant protein. (Expected MW is 22-150 kDa) Figure 3:Western blot analysis using LDLR mAb against HEK293 (1) and LDLR(AA: 22-150)-hIgGFc transfected HEK293 (2) cell lysate.
说明书	Product Datasheet Protocol
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