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ABCB1 Antibody

APR14754G Product Datasheet Protocol

货号	货期	规格 / 价格	询价
APR14754G		100 μl / ￥5450

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ABCB1 Antibody

品牌	Leading Biology	货号	APR14754G
产品分类	Monoclonal Antibodies	研究领域
产品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ABCB1 antibody.
分子量	141.5kDa
细胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein {ECO:0000255\|PROSITE-ProRule:PRU00441}
宿主	Mouse
种属反应性	Human
克隆号	6G11F8
亚型	IgG1
通用名	MDR1, PGY1
基因ID	5243
UniProt ID	P08183
功能	Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
总结	This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. ;
形式	Liquid. In PBS containing 0.02% sodium azide.
储存条件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
应用	WB, E
稀释方法	E~~1/10000 WB~~1/500 - 1/2000
别名	Multidrug resistance protein 1, 3.6.3.44, ATP-binding cassette sub-family B member 1, P-glycoprotein 1, CD243, ABCB1, MDR1, PGY1
图像	Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); Figure 1: Western blot analysis using ABCB1 mAb against human ABCB1 (AA: 632-693) recombinant protein. (Expected MW is 32.4 kDa) Figure 2: Western blot analysis using ABCB1 mAb against HEK293 (1) and ABCB1 (AA: 632-693)-hIgGFc transfected HEK293 (2) cell lysate.
说明书	Product Datasheet Protocol
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