品牌 |
Leading Biology | 货号 |
AMM08065G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SYCP3 antibody.
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分子量 |
27.7kDa
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Chromosome. Note=In tripartite segments of synaptonemal complexes, irrespective of whether these are synapsed or unsynapsed.
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宿主 |
Mouse
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种属反应性 |
Human
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克隆号 |
6F9B6
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亚型 |
IgG1
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通用名 |
SCP3
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基因ID |
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UniProt ID |
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功能 |
Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity).
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总结 |
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, FC, ICC, E
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稀释方法 |
E~~1/10000
WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
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别名 |
Synaptonemal complex protein 3, SCP-3, SYCP3, SCP3
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图像 |
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 1: Western blot analysis using SYCP3 mAb against human SYCP3 recombinant protein. (Expected MW is 37.2 kDa)
Figure 2: Western blot analysis using SYCP3 mAb against HEK293 (1) and SYCP3 (AA: 27-128)-hIgGFc transfected HEK293 (2) cell lysate. |
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说明书 |
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数量 |
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